THIS GRANT IS A CONTINUATION OF N000141510032 Molecular-scale Energy Transport and Computational Phenomena Enabled by DNA Nanotechnology
Abstract
The proposed research will investigate the fundamental properties of self-assembled nanoscalematerials which enable the fusion of computation with physical, chemical, and biologicalsystems. This work will leverage recent advances in the synthesis of DNA nanostructures andtheir application to drug delivery, computing, sensing, data storage, and cellular signaling thathave created new opportunities to study, and control, matter and the flow of information at amolecular level in a variety of physical contexts. Through the precise arrangement of molecularcomponents on DNA scaffolds, single-molecule characterization, and time-correlated singlephoton detection it is possible to design and test complex molecular sensing and computationalfunctionality in realistic micro-environments, e.g., in cell culture. This work will build on thesesuccesses to create new molecular structures which integrate computational capabilities into aphysical environment which could radically alter how we approach key national securityproblems, e.g., CBRN detection and mitigation. The broader impact of the work will alsocontribute to more secure and robust cyberphysical systems by enabling fundamentally newcomputational tools on physical objects and spaces. The impact will be significant andwidespread as the fundamental insights generated by this basic research reveal paths towarddesigning, understanding, and building molecular-scale systems which enhance and create newmission capabilities by bringing sophisticated computational power to nearly every niche of thephysical world.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Aug 12, 2016
- Source ID
- N000141612512
Entities
People
- Chris Dwyer
Organizations
- Duke University
- Office of Naval Research
- United States Navy