This grant is a continuation of N00014-13-1-0549 Rewiring a Microbial Chassis to Optimize Electrosynthesis
Abstract
The overall long-term objective of these studies is to develop a chassis microbe for high-rate microbial electrosynthesis, significantly improving the electrical contacts with cathodes and long-range electron transport through cathode biofilms. The research will focus on two organisms, Clostridium ljungdahlii and Geobacter sulfurreducens, which have complimentary components, that if combined, would make an excellent electrosynthesis chassis. Studies of the gram-positive C. ljungdahlii and the gram-negative G. sulfurreducens described in this proposal will identify diverse electronic microbial circuits for short-range cathode-to-cell electron transfer and long-range electron transport through cathode biofilms. The microbial electrical components revealed in these studies will serve as the building blocks for the de novo design of a superior microbial electrosynthesis organism and are expected to be useful components for engineering organisms for other applications that involve electrode-to-cell or cell-to-cell electron exchange
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Sep 23, 2016
- Source ID
- N000141612784
Entities
People
- Derek R. Lovley
Organizations
- Office of Naval Research
- United States Navy
- University of Massachusetts