An Integrated Coagulation Testing System for Millitary Health Research
Abstract
This proposal is relevant to the Office of Naval Research Department 34-342: Warfighter Protection and Applications Division (PM: Michael Given). The intent of this proposal is to purchase instruments needed to establish an integrated hemostasis testing system at theUniversity of Washington to support military-related research. The hemostatic testing system will support ongoing and future military-relevant research and will focus on determination of coagulation function using viscoelastic, protein, and cell-specific methods. The instruments will include: 1) ROTEM Delta rotational thromboelastometer, 2) Chrono-log Model 700 whole blood lumi-aggregometer, 3) Apogee A50-Micro flow cytometer, 4) TA Instruments Discovery HybridRheometer, and 5) Diapharma Ceveron Alpha integrated coagulation analyzer. In the short term, the hemostasis research system will support an ongoing study with strong military relevance. The study is a Department of Defense-funded study evaluating a novel fluid cocktail for field resuscitation of polytrauma with brain injury and hemorrhagic shock using a swine model (W81XWH-14-1-0020, PI: White). In the longer-term, the hemostatic testing system will support translational and clinical military-relevant trauma research protocols.The instruments will also support current research training programs focusing in trauma and hematology and will integrate with the Bloodworks Northwest research laboratories. This new capability will allow for expansion of research training programs and a new focus on the military-relevant fields of trauma and hemostasis. In summary, the requested instrumentationwill be used to establish an integrated hemostasis testing laboratory system that will greatly advance military-related research and education at the University of Washington.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Nov 23, 2016
- Source ID
- N000141613182
Entities
People
- Nathan J White
Organizations
- Office of Naval Research
- United States Navy
- University of Washington