3D printing of lab on pill microsystems
Abstract
Funds are requested to purchase a state of the art three-dimensional (3D) laserlithography system to print complex three-dimensional structures with sub-micronresolution. The printer will be used primarily to support the fabrication of lab-on-pillmicrosystems to autonomously sample the microbes living in our gut. This research effortis supported by the Office of Naval Research (ONR Award: N00014-16-1-2550, ProgramManager: Dr. Linda Chrisey). A growing body of evidence has implicated the human gutmicrobiome in a range of disorders, including obesity, inflammatory bowel diseases,cancer and cardiovascular disease. The proposed laser lithography system will enablefabrication of advanced pills that will enable sampling at higher spatial and temporalresolution even in small animals. The pills developed using this program will supportmicrobiome research activities not only in the research group of the PI, but also at variousacademic and DoD research labs including one at the Combat Feeding Directorate at theUS Army NSRDEC (PI: Ken Racicot, Award: TB 15-19).Beyond research efforts on gut microbiome, the proposed 3D printer will support severalother DoD research projects such as: (1) Development of a longer wavelength rectennafor energy harvesting longer wavelength~IR radiation. (PI: Vandervelde, ONR Award:N00014-15-1-2946); (2) Development of the SiGeSn materials system for optoelectronicapplications. Printer will be used to develop photonic test systems to evaluate thesematerials. (PI: Vandervelde, AFOSR Award: FA9550-15-1-0417, and Award: FA9550-15-1-0352); (3) Development of silk-based 3D bioprinting platform. Printer will be usedto develop sub-micron molds and struts for silk-based printing. (PI: Kaplan, AFOSRAward: FA9550-14-1-0015).The equipment will also support undergraduate and graduate research activities at TuftsUniversity. The equipment will be made available to external users from academia,government and industry to support other DoD research activities.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Mar 03, 2017
- Source ID
- N000141712317
Entities
People
- Sameer R Sonkusale
Organizations
- Office of Naval Research
- Tufts University
- United States Navy