Learning and Plasticity in Cortico-Hippocampal Circuits
Abstract
The hippocampus plays a critical role in the formation of episodic memories. The currentpredominant hypothesis is that memories are" gradually consolidated across distributed corticalnetworks under the influence of hippocampal activity. However, the nature and im"pact ofhippocampal influences on cortical circuits remains unknown. One of the main challenges hasbeen that hippocampal inputs res"ult in subthreshold changes in the membrane potential ofcortical neurons which are invisible to extracellular recordings, the tool" used in the vast majorityof previous studies.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Dec 20, 2017
- Source ID
- N000141812029
Entities
People
- Athanassios Siapas
Organizations
- California Institute of Technology
- Office of Naval Research
- United States Navy