A simple behavior test for measuring olfactory performance and GWAS to identify associated genetic markers
Abstract
Olfaction is the oldest of the vertebrate special senses and yet remains the least understood. In nearly all mammals, it plays vital roles in detecting threats and finding food, water, and potential mates. Domestic dogs represent an ideal species to better understand the mechanisms that determine olfactory functions and abilities. Olfactory sensitivity in canines is determined by genetic, neurological, physiological and developmental factors. In the present project, we propose to assess olfactory performances in dogs using a behavioral assay and subsequently these dogs participate in a genome-wide association study (GWAS) to determine the quantitative traits and genetic variation (to be performed by Prof. Robert Wayne s laboratory, UCLA, California, USA, which has considerable experience in canine genomics). To our knowledge this is a unique attempt to look at the genetic component of olfactory performance in dogs.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Aug 20, 2019
- Source ID
- N000141912512
Entities
People
- Ádám Miklósi
Organizations
- Eötvös Loránd University
- Office of Naval Research
- United States Navy