Understanding Extreme Response and Damage of Biological Materials

Abstract

Project AbstractUnderstanding Extreme Response and Damage of Biological Materials for Protective Measures and Biomimetic DesignTal CohenMassachusetts Institute of TechnologyTotal funds requested: $509,975Problem Overview and Impact on DoD Capabilities: The acute need for accurateand reliable prediction of the resilience of the human body in presence of extreme loading conditions, such as high accelerations, impact, and blast, is addressed in the proposed work. Its results will therefore have immediate implications on the design criteria for ship and aircraft maneuvering and Personal Protective Equipment (PPE), which directly influence the safety of individual service members.To address this need, the proposed work is geared to obtain comprehensive knowledge of the fundamental mechanisms of injury in extreme environments, by removing the limitations of available experimental techniques, developing experimentally validated constitutive rela- tions, and exploring specific applications which will further elucidate extreme phenomena and the effect of heterogeneity. At present, properties of biological tissue reported in the literature vary in orders of magnitude. This irreproducibility has not only hindered the abil- ity to obtain significant insights into the basic mechanisms of damage, but also prevents the maturation of large-scale computational platforms which are developed to simulate extreme response of the human body.Project Objectives: To combat this challenge the proposed work plan is designed to meet three primary objectives:1.Establish a new paradigm for testing and characterizing the extreme response and damage of soft and biological materials.2.Elucidate the basic mechanisms of deformation and damage at high rates and the role of material heterogeneity.3.Design constitutively matched biomimetic materials that exhibit similar nonlinear strain-stiffening response as their natural counterparts.

Document Details

Document Type
DoD Grant Award
Publication Date
Jun 17, 2020
Source ID
N000142012561

Entities

People

  • Tal Cohen

Organizations

  • Massachusetts Institute of Technology
  • Office of Naval Research
  • United States Navy

Tags

Readers

  • Critical Infrastructure Protection in CBRN and WMD Threats.
  • Nanocomposite Materials Science
  • Systems Analysis and Design

Technology Areas

  • Biotechnology