A wearable platform supporting high-frequency, in-vivo molecular measurements
Abstract
A wearable platform supporting high-frequency, in-vivo molecular measurements. To close the remaining knowledge gaps necessary to convert this technology into a convenient, wearable device by: 1) merging it with minimally-invasive, hollow microneedles that allow coupling to the interstitialfluid, 2) developing wearable, Bluetooth-enabled driving electronics, 3)developing calibration free sensor interrogation methods that will greatly ease the burdens associated with fabrication and use, and 4) demonstrating the device performance in initial human subjects trials. The successfuloutcome of the proposed research program would be the development and initial human subjects validation of a platform technology that would enhance warfighter performance under extreme operational conditions, and improve warfighter safety in times of medical need. It will do so by providing real-time, molecular-level read outs of multiple metabolites, hormones and biomarkersindicative of metabolism, health, and stress, thus providing an unprecedented, minute-to-minute window into physiological status via a wireless, wearable, minimally invasive and cost-effective device.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Aug 31, 2020
- Source ID
- N000142012764
Entities
People
- Kevin W Plaxco
Organizations
- Office of Naval Research
- United States Navy
- University of California, Santa Barbara