Decoding Olfactory Neural Codes
Abstract
Rodents rely heavily on olfaction and have developed exceptional abilities to detect odorants in their environment. High performance in odor detection and discrimination is achieved even in the face of large variations in intensity and context, as is the case when animals encounter odor plumes when exploring an environment. Odors are represented by spatiotemporal patterns of activity across mu ltiple brain areas, from the olfactory bulb, to piriform cortex, and the hippocampus. We propose to use novel high density 3-D array s of electrodes to record activity in the olfactory bulb and the hippocampus in behaving mice in order to characterize the populatio n neural codes for olfactory stimuli and to determine how these codes depend on brain state. A deeper understanding of olfactory neu ral codes will facilitate the development of biology-basedsensors for standoff detection of explosive materials.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Oct 20, 2021
- Source ID
- N000142112928
Entities
People
- Evguenly Lubenov
Organizations
- California Institute of Technology
- Office of Naval Research
- United States Navy