Nanoindentation system for the comprehensive mechanical characterizations of soft biological tissues
Abstract
FY21 DURIP Funds for:Nanoindentation system for comprehensive mechanical characterizations of soft biologicaltissues with heteroge nous propertiesIn the DURIP proposal, we request funding to purchase a nanoindentation system forcharacterizing and analyzing the distribution of mechanical properties of soft biological tissues.Such characterizing capabilities are critical for constructing a high-fidelity human digital twin,which are indispensable for the numerical simulations of human bodies subject to variousmechanic al loadings. To demonstrate the new research capabilities in the PIs lab, in the project,we will use the nanoindentation system to obtain high resolution maps of frequency-dependentloss modulus, storage modulus, phase lag angle, water mobility and fracture toug hness of porcineliver and kidney.The nanoindentation system will also greatly enhance the research capabilities of currentlyfunde d projects by the DoD that the PI has been involved in. Those DoD funded projects includeinvestigating cavitation in soft materials and tissues, designing artificial muscle for biomimeticsoft robots and creating stimuli-responsive mechanical metamaterials. The r equestednanoindentation system will allow us to accurately characterize the local mechanical properties ofvarious materials in all those ongoing projects. We will also make the nanoindentation systemaccessible to other researchers from the PIs institute. It ha s been evident that their researchprojects funded by the DoD or other agencies can also greatly benefit from the capabilities of th erequested nanoindentation system.Furthermore, the PI will introduce the nanoindentation system, the corresponding experimentalte chnique and the underlying theoretical foundations in the courses being regularly taught at UCSDby the PI. The undergraduate and gr aduate researchers working in the PIs lab will receiveprofessional trainings on operating the facility and conducting data analysi s. Such experience canbe extremely valuable for those students who may work on the areas of interest to the DoD.It is understood t hat any developmental items and specially designed parts, components,accessories and attachments fabricated under any Department of Defense award resulting from thisproposal are being developed for civil or potential military applications.Budget JustificationT he requested budget is completely based on the quote from the vendor as attached. 100%of the requested fund will be used to purchas e the Nanoindentation System as listed in theproject narrative. Additional cost for the maintenance of the Nanoindentation System i n thefuture will be covered by future federal funds such as the funds from NSF, DOE and DoD.In addition to that, the Department of Mechanical and Aerospace Engineering at UCSDcommits to provide a one-year fellowship to a graduate student to conduct the research described in the project narrative.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Oct 22, 2021
- Source ID
- N000142112935
Entities
People
- Shengqiang Cai
Organizations
- Office of Naval Research
- United States Navy
- University of California, San Diego