Extracting High-rate Material Properties of Biological Tissue Using Inertial Microcavitation Rheomet
Abstract
Approved for Public ReleaseAccurate predictions of human soft tissue response to mechanical loading requires accurate resolution of,its underlying properties at the given loading rate. While determination of low, quasi-static strain rate properties is relatively s,traightforward and established, high rate material characterization for blast, ballistic and blunt exposure are much more challengin,g to acquire and are therefore still largely lacking in the literature. To date, many of the material properties featured in human i,mpact and injury simulations were derived from either low-rate measurements or a very limited set of high-rate data, which limits th,eir innate predictive power and accuracy. To address this challenge, the current proposal continues and extends the study from the p,revious ONR performance period utilizing a recently developed inertial microcavitation rheometry (IMR) technique that has shown to b,e minimally invasive, accurate and capable of extracting high loading rate material properties from soft polymer and tissue material,s. The application featured herein is the mechanical characterization of the high-rate mechanical properties of swine brain, kidney,and liver tissue at blunt, ballistic and blast loading rates. In addition, we aim to examine the thermal behavior of the same biolog,ical tissues at physiologically relevant temperatures via our well-established digital image correlation techniques. We will employ,the latest state-of-the-art DIC techniques to track the expansion of brain, kidney and liver swine tissue under equilibrated tempera,tures ranging from 30 - 45 degrees Celsius using a custom-designed temperature chamber.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Mar 05, 2022
- Source ID
- N000142212107
Entities
People
- Christian Franck
Organizations
- Office of Naval Research
- United States Navy
- University of Wisconsin System