Assessment of multi-system responses to acute stressors in humans using Ultrasound
Abstract
Approved for public release:This application requests funding for the purchase of an ultrasound system for human physiology research at the University of Oregon. This state of the art system will be a shared resource that will directly benefit the work in 9 laboratories across multiple departments (Human Physiology and Knight Campus for Accelerating Scientific Impact) at the University of Oregon by improving the capabilities to conduct research and educate emerging scientists in areas related to musculoskeletal morphology/mechanics as well as movement of blood and perfusion of vital tissues during challenges to homeostasis in healthy humans and in humans with various diseases. The ultrasound system will allow our group to measure musculoskeletal stiffness/compliance as well as morphology and composition (contractile and non-contractile tissues). In separate but related experiments, we will be able to track blood flow in large conduit arteries and in the microcirculation. The PrincipalInvestigator and Co-Investigators will use this capacityto enhance the capabilities of their well-established research programs related to musculoskeletal, cardiovascular, respiratory/pulonary, and thermoregulatory responses to exercise, environmental stress, and tissue injury and further improve the training of future integrative human physiology researchers at the University of Oregon. When used in conjunction with the state-of-the-art research instrumentation available within our group including the newly constructed Environmental Chamber and Motion Analysis labs at the Bowerman Sports Science Center at the University of Oregon, the ultrasound system will facilitate investigations in a broad range of areas associated with human performance. These investigations have the potential to contribute directly to the overall goals of the Department of Defense through the Army Research Office, Office of Naval Research and Air Force Office of Scientific Research by fostering the pursuit of basic and translational science regarding how humans respond and adapt to survive challenges to homeostasis in health and disease.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Jan 12, 2023
- Source ID
- N000142312228
Entities
People
- Damien Callahan
Organizations
- Office of Naval Research
- United States Navy
- University of Oregon