Studying Transport-induced Blood Clot Embolization as a Fluid-Structure Interaction Phenomenon?
Abstract
The proposed instrumentation combines a pulsatile flow pump, a shake table, and a simultaneous 3D Digital Image Correlation (3D DIC) and 3D Particle Image Velocimetry (3D PIV) system. Together, they function as a modular and therefore widely applicable experimental framework to study fluid-structure interaction problems. This system will serve both the principal investigator on this proposal, Dr. Manuel K. Rausch, as well as the scientific and broader community of the University of Texas at Austin. Specifically, the principal investigator will use this equipment to further our understanding of transport-induced blood clot embolization toward establishing safe ride standards for autonomous transportation of injured warfighters. To this end, Dr. Rausch will study the risk of embolization under non-transport conditions and under transport conditions. His studies will combine the 3D DIC/PIV system to mechanistically delineate the interactions between solid (blood clot) and fluid (blood) that lead to fracture and embolization. He will also use this instrumentation to improve undergraduate and graduate education at the University of Texas at Austin. This will be achieved by enhancing students’ laboratory courses and through hands-on training on technologies that will prepare the students for careers in industry and in the military. To further broaden the impact of this instrumentation, Dr. Rausch plans to also incorporate the instrumentation into outreach activities with a Department of Defense affiliated outreach program in Austin, TX. Finally, through its wide applicability, this instrumentation will also further research programs at the University of Texas at Austin that are currently sponsored by the Department of Defense. Example projects with more than $5 Million in Department of Defense funding range from novel cardiovascular monitoring systems to fluid-structure interaction problems in hypersonic flight, and sediment dynamics in nearshore ammunition burial sites.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Jan 12, 2023
- Source ID
- N000142312236
Entities
People
- Manuel K Rausch
Organizations
- Office of Naval Research
- United States Navy
- University of Texas at Austin