SCI: Bridging the Gap with Biological and Electronic Systems
Abstract
This effort aims to dramatically improve the functional trajectory of individuals with spinal cord injury (SCI) through a multi-stage repair strategy that covers the acute-subacute-chronic care continuum with synergistic therapeutic approaches unique to this effort: i) a near-infrared spectrometry sensor that interrogates the SCI penumbra to enable neuroprotection and stabilization of the cord acutely, (ii) a neural stem cell/scaffold graft that promotes regeneration to bridge the gap subacutely & chronically, and (iii) neurotechnologies for closed-loop control of targeted electrical spinal stimulation (TESS) that mimics the physiological activation of spinal circuits to mediate functional recovery in the chronic phase.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Jan 06, 2022
- Source ID
- N660012024046
Entities
People
- Karen A Moxon
Organizations
- Defense Advanced Research Projects Agency
- Naval Information Warfare Center Pacific
- University of California, Davis