HEPIUS: Holistic electrical, ultrasonic, and physiological interventions unburdening those with spinal cord injury
Abstract
The HEPIUS system of systems consists of two implants: a multimodal, multi-functional spinal cord implant (MUSIC), and an acute cerebrospinal fluid management implant (ACMI). MUSIC is a completely novel epidural implant capable of performing ultrasound imaging and stimulation, as well as electrical recording and stimulation in patients with acute spinal cord injury (SCI). MUSIC offers unique capabilities for SCI monitoring, neuromodulation, and regeneration. This implant shall be placed directly over the injury site (epidurally), providing the ability to record and stimulate the spinal cord above, below, and at the site of the injury. ACMI, an advanced version of the lumbar drainage catheters currently used in the subarachnoid space, shall allow monitoring of cerebrospinal fluid (CSF) parameters, optimizing spinal cord perfusion. MUSIC, implanted at the site of injury, shall make it possible to stimulate and record across the site of injury, enhancing neuromodulation in the acute phase of SCI.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Jan 06, 2022
- Source ID
- N660012024075
Entities
People
- Nicholas Theodore
Organizations
- Defense Advanced Research Projects Agency
- Johns Hopkins University
- Naval Information Warfare Center Pacific