MEDICAL BIOLOGICAL DEFENSE (BASIC RESEARCH)

Abstract

This project (TB1) supports basic research of vaccines, diagnostic tools, and therapeutic drugs to provide effective medical defense against validated biological threat agents including bacteria, toxins, and viruses. Research efforts advance promising innovative biotechnology approaches with the potential to rapidly identify, diagnose, prevent, and treat disease due to exposure to biological threat agents. This project supports core science efforts that may be applied to biological defense capability areas, such as Pretreatments, Diagnostics, and Therapeutics. This project includes basic research to support Transformational Medical Technologies (TMT) efforts. The program was launched to respond to the threat of emerging or intentionally bioengineered biological threats. Research efforts evaluate the molecular characteristics of the interaction between host and pathogen, characterize the host's response to infection/intoxication and identify common mechanisms and/or pathways. The research also studies the correlates of immunity (common response against different pathogens), and looks for pre-symptomatic bio-markers. In FY13, all Project TB1 research efforts are re-aligned to Project LF1 - Life Sciences (Basic Research).

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Document Details

Document Type
Project
Publication Date
Oct 01, 2014
Source ID
TB1_0601384BP_1_0400_PB_2014

Tags

Readers

  • Critical Infrastructure Protection in CBRN and WMD Threats.
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.

Technology Areas

  • Biotechnology

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