MEDICAL CHEMICAL DEFENSE (ATD)
Abstract
This project (TC3) supports the advanced development of medical countermeasures to include prophylaxes, pretreatments, antidotes, skin decontaminants and therapeutic drugs against identified and emerging chemical warfare threat agents. Analytical stability studies, safety and efficacy screening, and preclinical toxicology studies are performed prior to full-scale development of promising pretreatment or treatment drug compounds. Entry of candidate pretreatment/prophylaxes, therapeutics, and diagnostic technologies into advanced development (i.e., efforts funded in Budget Activities 4 and 5) is facilitated by the development of technical data packages that support the Food and Drug Administration (FDA) Investigational New Drug (IND) application and licensure processes, as well as Department of Defense (DoD) acquisition regulations. Categories for this project include Pretreatments, Diagnostics, and Therapeutics to address Chemical Warfare Agent (CWA) and Non-Traditional Agents (NTAs) exposure. In FY11, all NTA-dedicated research was re-aligned into specific capability areas within this project in order to ensure a focused effort on this high priority area.
Document Details
- Document Type
- Project
- Publication Date
- Oct 01, 2012
- Source ID
- TC3_0603384BP_3_0400_PB_2012
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