A New Discovery for Antibiotic Therapy Targeting the Biofilm Core
Abstract
Soldiers in the battlefield suffer from traumatic injuries that become infected. These infections are often caused by bacterial contaminants that in live in complex communities called biofilms. Biofilms are very tolerant to traditional antibiotics, primarily because the bacteria living inside the colony begin to behave differently in response to their closed-off environment. We have discovered a chemical compound that specifically attacks these more-problematic bacteria living inside the biofilm, thus providing a new way to improve infection outcomes in Soldiers and civilian patients who are wounded.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Mar 10, 2021
- Source ID
- W81XWH2010069
Entities
People
- Nicholas Ashton
Organizations
- United States Army
- University of Utah