Lung Macrophage Populations and Functions in COPD-Susceptible Smokers

Abstract

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease that affects only a fraction of those who smoke tobacco. The origin of this variability in susceptibility to develop COPD is unclear, but understanding its underlying biology has important implications for our ability to design suitable preventative and therapeutic strategies for its management. This Department of Defense discovery research proposes to develop methodologies and generate preliminary data needed to lay the foundation for a large study that would investigate the underlying biological susceptibility of those who smoke tobacco to develop COPD.

Document Details

Document Type
DoD Grant Award
Publication Date
Mar 10, 2021
Source ID
W81XWH2010158

Entities

People

  • Mehrdad Arjomandi

Organizations

  • United States Army
  • University of California, San Francisco

Tags

Fields of Study

  • Medicine

Readers

  • Immunology and Pathology
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Systems Analysis and Design