Epidural Stimulation and Resistance Training for Overground Locomotion After Spinal Cord Injury
Abstract
Public Spinal cord injury (SCI) is a devastating health problem for tens of thousands of military personnel, Veterans, and civilians annually. Many persons with SCI must use a wheelchair for their entire lives. A new scientific breakthrough called “lumbosacral epidural stimulation” or “ES” can help people with SCI to stand, step, and even walk again. At present, for ES to work, people must train with a specialized treadmill that requires several other qualified personnel to train them, which makes it hard for many people with SCI to benefit from this technology. On the other hand, there are wearable “robot suits” that can be used with ES, which would make it easier to use. Our research team has already used this “ES Robot Suit” for 3 months in one person with tetraplegia and showed remarkable improvements in motor control. Furthermore, we are aiming to enhance over-ground motor recovery by adding 6 months of resistance training (RT). The addition of RT will likely enhance muscle quality, as indicated by increasing lean mass, peak torque, and increase sensory flux to the central nervous system. Other additional benefits may include improvement in cardiovascular profile and bladder functions. The specific objectives of the current proposal are to compare the impact of EAW+ES following the improvement of lower extremity muscle quality compared to those who will only undergo EAW+ ES without conducting RT on motor recovery, cardio-metabolic health, and bladder control in persons with complete SCI. At the conclusion of the current proposal, the work will be readily available for translation into clinical setting to serve Veterans and civilian survivors with SCI.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Mar 10, 2021
- Source ID
- W81XWH2010845
Entities
People
- Ashraf S Gorgey
Organizations
- United States Army
- Virginia Commonwealth University