An Intravenous Polymer Hemostat for Noncompressible Hemorrhage and Traumatic Brain Injury

Abstract

This project directly addresses the focus area, Innovative and novel technologies that can stop life-threatening bleeding in the torso region of patients who are delayed in receiving definitive surgical care. The goal of this project is to test the effect of a novel intravenous hemostatic biopolymer on noncompressible truncal hemorrhage and traumatic brain injury (TBI) in experimental models. This project seeks to test its effects on critical aspects of the pathophysiology of polytrauma, including TBI, blood loss, and resuscitation during simulated tactical combat casualty care. Results will be used to guide further development of the biopolymer for translation to human use within the next 5-10 years and will ultimately benefit Service Members and the public by providing a new and improved therapy for TBI and severe trauma casualties.

Document Details

Document Type
DoD Grant Award
Publication Date
Dec 28, 2022
Source ID
W81XWH2210063

Entities

People

  • Nathan J White

Organizations

  • United States Army
  • University of Washington

Tags

Fields of Study

  • Medicine

Readers

  • Defense Technology Research and Development.
  • Trauma Surgery or Emergency Medicine.
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.