Computationally Designed IL-10 Mutants for the Treatment of Inflammatory Bowel Diseases

Abstract

Inflammatory bowel disease (IBD) is a common public health problem affecting millions of Americans including military Service Members and Veterans. This project takes the advantages of cutting-edge technologies of computational protein design and advanced gene therapy in drug discovery and delivery areas to develop novel drugs with higher efficacy and safety profile for the treatment of IBD. Successful completion of this project will pave the way for their clinical applications.

Document Details

Document Type
DoD Grant Award
Publication Date
Dec 28, 2022
Source ID
W81XWH2210065

Entities

People

  • Sihong Song

Organizations

  • United States Army
  • University of Florida

Tags

Fields of Study

  • Medicine

Readers

  • Oncology

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech