MoD Molecules on Demand

Abstract

The proposed effort seeks to develop an integrated on-demand system (termed Molecules on Demand) for the synthesis and purification of a broad class of organic molecules The proposed MOD system will leverage the unique capabilities, efficiency, robustness, and scalability of flow chemistry to render a broader class of organic materials, prepared via an on-demand steady state manner, than currently possible with on-demand batch processes. To demonstrate proof-of-concept, the PIs will develop the corresponding chemistry and system components for the MOD approach. Specifically, the Chemistry team will investigate the appropriate flow chemical reactions to incorporate into the MOD system as well as the boundary conditions and limitations of different classes of chemical reactions. Concurrently, the Systems team will explore novel pumping mechanisms to ensure continuous flow of solvents and reactions solutions throughout the MOD system and demonstrate the ability to monitor flow rates. Each of these studies will aid in the design and fabrication of the MOD system and the system will be tested to demonstrate the on-demand, automated synthesis of two classes of chemical processes: 1) controlled polymerization and 2) multistep synthesis.

Document Details

Document Type
DoD Grant Award
Publication Date
Jan 12, 2017
Source ID
W911NF1510183

Entities

People

  • Timorthy Jamison

Organizations

  • Army Contracting Command
  • Massachusetts Institute of Technology
  • Office of the Secretary of Defense

Tags

Readers

  • Distributed Systems and Data Platform Development
  • Organic Chemistry