Comparative Studies of Temporal Patterns among Biomarker Groups during Conditions Relevant to Military Duties, Part 1: Physical Exercise, Sweat Vs Blood Plasma
Abstract
Real-time evaluation of fitness for duty could reduce injuries and errors in military ope rations. This may become practical with the development of unobtrusive biomarker measures of stress, fatigue, cognitive function, and physical trawna that do not interfere with mission performance. This proposal is aimed at reducing the limitations of the current state-of-the-art in biomarker measurement by (1) measuring biomarker levels in sweat instead of blood plasma, (2) identifying correlations among groups of biomarkers to improve specificity and. create indices for each condition of interest (e .g., fat igue) and (3) determining time-based patterns of variation in these biomarker indices to further increase specificity and detection of trends at earlier stages. As compared to the current blood plasma biomarker profiling, the non-invasive nature of sweat analysis could enable sampling and analysis when and where blood draw is not convenient or not possible during mission.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Jan 12, 2017
- Source ID
- W911NF1510255
Entities
People
- Esther Sternberg
Organizations
- Army Contracting Command
- Office of the Secretary of Defense
- University of Arizona