Organic-mediated Mineral Transport and Force Transduction in an Ultrahard Biological Composite: Biochemistry 8.1
Abstract
We will examine the ultrastructure of the stylus and partially mineralized teeth and the chemistry involved in the biomineral formation as outlined according to the following investigations: 1. An understanding of the structure and chemistry of the organic stylus and radular belt (in functional teeth) with a complementary mechanical investigation (combined modeling and experimental) of these complex structures that interfaces with mineralized teeth and enables force transduction. 2. Investigation of the mechanism of mineral transport within the stylus and its effect on the formation of the teeth. 3. A thorough investigation of the underlying organic framework (structural and chemical) that regulates nucleation and growth of ferrihydrite and its transformation to magnetite in the teeth. 4. Fabrication of biomimetic multifunctional structures through organic fiber assembly and in-vitro mineral transport studies to understand organic-mineral interactions and force transduction capabilities.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Oct 30, 2018
- Source ID
- W911NF1510306
Entities
People
- David J Kisailus
Organizations
- Army Contracting Command
- United States Army
- University of California, Riverside