Analysis of Stable Isotopes by Triple Quadrupole GC/MS (GC-QQQ) for the Determination of Metabolic Flux and Stress Resistance (Resiliency)

Abstract

The instrument proposal was for acquisition of a Triple Quadrupole GC/MS (GC-QQQ) to markedly increase throughput, method development, and current stable isotope analysis capabilities. Using the GC-QQQ purchased, we have made progress in establishing sensitive approaches to assessing both metabolism and stress resistance using a variety of models (in vitro, animal, and human subjects) to address our hypotheses. The expanded instrumentation in our laboratory has led to new collaborations, new proposal submissions including 2 in review at ARO, 6 new publications, and many more in preparation/review. We now provide expanded student research training including those via HSAP/URAP mechanisms.

Document Details

Document Type
DoD Grant Award
Publication Date
Jan 30, 2017
Source ID
W911NF1510337

Entities

People

  • Benjamin Miller

Organizations

  • Army Contracting Command
  • Colorado State University
  • United States Army

Tags

Readers

  • Analytical Chemistry
  • Oncology (Cancer Research).
  • Research Science/Academic Research