Magnetoelectronic Sensors for Gasotransmitters
Abstract
The discovery of gasotransminers-gaseous molecules involved in biological signaling-has revolutionized our understanding of intracellular communication. Although three gasotransmitters (nitric oxide, carbon monoxide. and hydrogen sulfide) are currently known. their complex biological function is not fully understood due to a limited set of analytical tools for probing this function. I propose 10 address this analytical challenge or detecting gasotransmitters by integrating two established concepts-chemiresistance and magnetoresistance-into a single portable sensor array. The experimental approach relies on developing new materials and a new paradigm in signal transduction and amplification in solid-state chemical sensors that takes advantage of two fundamental properties of electrons: charge and spin. The molecular design towards this goal employs bottom-up synthesis of multifunctional responsive two-dimensional (2D) nanomaterials capable of changing their electrical resistance in response 10 a chemical stimulus due to perturbations of both electronic and magnetic properties. These two perturbations will work together to produce an additive amplified effect on the electrical resistance of multifunctional materials embedded within solid state sensors. This work will further the fundamental understanding of spin-coupled charge transport through nanomaterials, and enable development of highly sensitive and selective electronic sensing devices. Materials and methods emerging from this work may also find applications in monitoring of environmental pollution, and in magnetoelectronic information storage.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Oct 16, 2018
- Source ID
- W911NF1710398
Entities
People
- Katherine A. Mirica
Organizations
- Army Contracting Command
- Dartmouth College
- United States Army