Real time imaging system to study vital sub-cellular organelles
Abstract
Funds are requested for purchase of an optical imaging system to study sub-cellular organelles in their vital dynamic state. This will be a major upgrade to our atomic force microscope, allowing simultaneous optical imaging to complement scanning microwave microscopy for real-time imaging of vital cells and sub-cellular organelles. This will enable long-term research on the structure and dynamics of sub-cellular organelles such as mitochondria and their electrophysiological role. Currently supported as well as planned research for this equipment include: 1) Scanning microwave microscopy of vital mitochondria, 2) Studies of cancer and apoptosis, 3) Integration of olfactory proteins with nanoelectronics using single ion channel electrophysiology; 4) Study of extracellular vesicles in human serum; 5) more generally, biotronics i.e biology and the physical world.
Document Details
- Document Type
- DoD Grant Award
- Publication Date
- Jun 17, 2019
- Source ID
- W911NF1910369
Entities
People
- Peter J Burke
Organizations
- Army Contracting Command
- United States Army
- University of California, Irvine