Implement Bio-amplitude Neuromorphic Electronics In Biointerfaces

Abstract

The long-term goal of the research is to improve the intimacy in bioelectronic interfaces, in which electronics can directly ÔtalkÕ to biosystems (e.g., cell, tissue, organ) without additional ÔtranslationÕ. The general approach is to develop and implement biomimetic or neuromorphic electronics that emulate the functionalities in biological components (e.g., synapse and neuron). A critical step is to realize amplitude matching between electronics and biosystems which work with a signal amplitude approaching the thermodynamic limit (e.g., <100 mV). Traditional electronics or neuromorphic devices work at 10? the bio-amplitude and hence fall short of the requirement. The objective here is to develop and implement bio-amplitude (e.g., <100 mV) neuromorphic electronics that strictly comply with bio-computation to fundamentally fill the gap. Our immediate goal is to validate that biological signals are able to directly drive constructed bio-amplitude neuromorphic electronics for self-sustained interfacing. The research is expected to advance closed-loop bioelectrionic interfaces, which will contribute to advanced human technologies, including, e.g., neurological disease cure, prosthetics, and performance augmentation. It is also expected to support development in hybrid bio-bots and living microsystems.

Document Details

Document Type
DoD Grant Award
Publication Date
Jan 04, 2021
Source ID
W911NF2110051

Entities

People

  • Jun Yao

Organizations

  • Army Contracting Command
  • United States Army
  • University of Massachusetts Amherst

Tags

Readers

  • Aerospace Propulsion Engineering.
  • Integrated Circuit Design and Technology.
  • Neuroscience

Technology Areas

  • Biotechnology
  • Microelectronics
  • Microelectronics - Microelectromechanical Systems