DoD (HBCU/MSI-Equipment/Instrumentation): Acquisition of HPLC-MS/MS to Accelerate Multidisciplinary Research, Education and Training Capabilities at UDC

Abstract

This proposal is for capacity building at the University of the District of Columbia (UDC), an Historically Black College and University (HBCU) and the only public university as well as Servicemembers Opportunity College (S.O.C.) in the nationÕs Capital. This will accelerate multidisciplinary research, education, and training capabilities of UDC based on collaboration among faculty members of School of Engineering and Applied Sciences (SEAS), College of Agriculture, Urban Sustainability, and Environmental Science (CAUSES), and the College of Arts and Sciences (CAS). This proposal seeks to procure a liquid chromatography mass spectrometer (LC-MS/MS) with supplementary solid-phase extraction (SPE) and flash chromatography systems from the Department of Defense (DoD). The PIs of the proposal are from the Department of Civil Engineering SEAS, the Water Resources Research Institute (WRRI) of CAUSES, and the Programs of Chemistry and Biology of CAS. This collaboration includes projects on a) pharmaceuticals, pesticides, cyanotoxins, and PFAS treatment, b) evaluation of triorganotin complexes (inhibitors), c) investigation of DNA binding of emetine & metabolites, d) development of fluorescent probes, e) neurological metabolomic investigation, f) identification of toxin-induced metabolites and g) investigation of cancer-derived exosomes. The projects proposed span among different priority areas and goals of specific programs of Army Research Office (ARO) (e.g. environmental chemistry, microbiology, molecular structure and dynamics, genetics etc) and Office of Naval Research (ONR) (e.g. environmental quality program, biological and physiological monitoring, functional polymeric and organic materials etc). This proposal also outlines educational expansions at different departmental levels where our undergraduate and graduate students including some veterans will benefit directly from this instrument, and outlines utilities for summer programs and community service. Several existing courses have been identified and new courses have been proposed at different departmental levels, including Course- Based Undergraduate Research Experiences (CUREs). The PIs are expected to develop course toolkit in their respective areas to engage middle and high school teachers and provide them builtin course modules with training through summer workshops to get replicated in their respective high school/middle school classes. Overall, this equipment, with its supplementary systems, will provide cutting-edge multidisciplinary research exposure to our UDC students and will prepare them as a next-generation workforce. This instrumentation will be an exciting addition to UDCÕs emerging research aspiration and will open opportunities to pursue additional funding from different priority areas of DoD for faculty members of UDC. Thus, the projects proposed will stimulate multidisciplinary collaboration and enhance research and engineering capabilities of UDC in areas important to national defense and security.

Document Details

Document Type
DoD Grant Award
Publication Date
Aug 11, 2022
Source ID
W911NF2210191

Entities

People

  • Hossain Azam

Organizations

  • Army Contracting Command
  • Office of the Secretary of Defense
  • University of the District of Columbia

Tags

Readers

  • Analytical Chemistry
  • Research Science/Academic Research
  • STEM Education

Technology Areas

  • Biotechnology