Biological Adaptation, Assembly and Manufacturing

Abstract

The Biological Adaptation, Assembly and Manufacturing program is examining the structure, function, and informational basis underlying biological system adaptation, and the factors employed by the organism to assemble and manufacture complex biological subsystems. The unique stability afforded biological systems in their ability to adapt to wide extremes of physical and endurance (e.g., heat, cold, and sleeplessness) parameters will be examined and exploited in order to engineer stability into biological systems required for the military (such as blood, bioengineered tissues or other therapeutics). In addition, the fault tolerance present in biological systems will be exploited in order to assemble and manufacture complex physical and multi-functional systems, both biological and abiotic (such as tissue constructs designed for reconstructive surgery). These systems include novel load-bearing bio-interactive materials and composites for repair of severe hard tissue trauma, including complex bone fractures. A key new antibody technology will develop the ideal antibody master molecule for use in unattended sensors that maintains high temperature stability and controllable affinity for threat agents. Using the Freytag triangle structure, the interplay of narratives or stories may reveal how they tap into an array of mechanisms implicated in memory, reasoning, and strategy behavior. Applications to Defense systems include the development of chemical and biological sensors; tools for strategic military decision-makers involved in public relations and information operations, and improved warfighter battlefield survivability.

Document Details

Document Type
Accomplishment
Publication Date
Oct 01, 2013
Source ID
a21d68446eaeee2a2332c3418a8f8a7f

Tags

Readers

  • Molecular Genetics
  • Nanocomposite Materials Science
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology

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