Faster Short Tandem Repeat (FaSTR) Human Deoxyribonucleic Acid (DNA) Profiling System
Abstract
To date, rapid DNA analysis systems have relied on pneumatics and mechanical valves for microfluidic movement which results in bulky hardware and assay times greater than 60 minutes. The FaSTR DNA instrument exploits centrifugally-driven microfluidics to eliminate mechanical valves and pressure-driven flow, and allows commercial off the shelf electronics to facilitate sample preparation, polymerase chain reaction, and integration with electrophoresis (the movement of charged particles in a fluid or gel under the influence of an electric field). This paradigm shift for microfluidic technology radically reduces the form factor, analysis time, and cost of the system. The FaSTR project will produce the first truly portable, rapid DNA analysis instrument capable of generating DNA profiles from “sample in” to “answer out” in less than 30 minutes and provide a match probability of 1 in 55 billion people.
Document Details
- Document Type
- Accomplishment
- Publication Date
- Oct 01, 2018
- Source ID
- bd10da87d2ac8cbd96726efa24cb0404