12) Techbase Med Bio - Therapeutics

Abstract

Multiagent (Broad Spectrum) Medical Countermeasures: Continues efforts previously funded under the Transformational Medical Technologies Initiative to develop candidate countermeasures for Hemorrhagic Fever Virus (HFV) and Intracellular Bacterial Pathogen (IBP). Focuses on the initiation and completion of preclinical studies for candidate countermeasures, to include safety, toxicity, efficacy, and scalability work in accordance with the product's intended use. The ability to formulate Good Manufacturing Practices (GMP), pilot lots and further mature promising drug candidates will be the focus of activities in this capability area. The preclinical drug discovery process culminates in the submission of an Investigational New Drug (IND) application to the Food and Drug Administration (FDA), to determine if candidate countermeasures are suitable for safety evaluation in humans. In FY14, research under this thrust area will be transitioned into the Bacterial and Viral Therapeutics program under BA3 Techbase Med Defense - Bio CM (TM3).

Document Details

Document Type
Accomplishment
Publication Date
Oct 01, 2014
Source ID
caad7ad91ae69307f8e53fb81c243e24

Tags

Readers

  • Critical Infrastructure Protection in CBRN and WMD Threats.
  • Infectious Disease/Epidemiology
  • Systems Analysis and Design

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