Analytics and Adaptation of Human Resilience

Abstract

The Analytics and Adaptation of Human Resilience program will explore new methods to maintain and optimize warfighter health in response to environmental insults such as new and emerging infectious diseases. Projects in this area will apply recent advances in comparative biology, genetic sequencing, omics technologies, and bioinformatics to develop new tools for modulating health to ensure warfighter readiness. One approach to achieve this goal is identifying the fundamental mechanisms that enable certain species to be tolerant to various environmental insults. Genomic and physiological analyses of a wide array of resilient animal species may be combined with sophisticated algorithms to identify important patterns of survival. By analyzing patterns in the underlying variability of host responses for resilient animals, one may formulate a survival blueprint to restore and maintain warfighter homeostasis in response to infection. This approach is orthogonal to traditional infectious disease research, which primarily relies on reducing the pathogen load through drug intervention. Projects within this program may enable discovery of novel methods to optimize human health against infectious disease such as multi-drug resistant pathogens.

Document Details

Document Type
Accomplishment
Publication Date
Oct 01, 2016
Source ID
d02482cf62606ba5f7a652014cda44e3

Tags

Fields of Study

  • Biology

Readers

  • Defense Technology Research and Development.
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Infectious Disease/Epidemiology

Technology Areas

  • Biotechnology

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