Blood Pharming - Medical
Abstract
The Blood Pharming program objective is to develop an automated culture and packaging system that yields transfusable levels of universal donor red blood cells (RBCs) from progenitor cell sources. The goal is to produce 100 units of universal donor (Type O negative) RBCs per week for eight weeks in an automated closed culture system using a renewing progenitor population, and to demonstrate a two hundred million-fold expansion of progenitor cell populations to mature RBCs. The program will capitalize advances in cell differentiation, expansion, and bioreactor technology developed early in the program. Successful completion of the Blood Pharming effort will provide a safe donorless blood supply that is the functional equivalent of fresh donor cells, satisfying a large battlefield demand and reducing the logistical burden of donated blood in theater.
Document Details
- Document Type
- Accomplishment
- Publication Date
- Oct 01, 2012
- Source ID
- d3709756333d45cef13dd7153b5acbe8