In vivo Nanoplatforms (IVN)
Abstract
The In vivo Nanoplatforms (IVN) program seeks to develop the nanoscale systems necessary for in vivo sensing and physiologic monitoring and delivery vehicles for targeted biological therapeutics against chemical and biological (chem-bio) threat agents. The nanoscale components to be developed will enable continuous in vivo monitoring of both small (e.g., glucose, nucleic acids, biomarkers) and large molecules (e.g., biological threat agents). A reprogrammable therapeutic platform that targets gene regulatory sequences will enable tailored therapeutic delivery to specific areas of the body (e.g., cells, tissue, compartments) in response to traditional, emergent, and engineered threats. The key challenges to developing these systems include safety, toxicity, biocompatibility, sensitivity, response, and targeted delivery. The IVN program will have diagnostic and therapeutic goals that enable a versatile, rapidly adaptable system to provide operational support to the warfighter in any location.
Document Details
- Document Type
- Accomplishment
- Publication Date
- Oct 01, 2017
- Source ID
- d3b8572d2f229e9e417edcb015b30d5d
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- Root: ELECTRONICS TECHNOLOGY