Gene Editing Enabled Diagnostics & Biosurveillance
Abstract
The Gene Editing Enabled Diagnostics & Biosurveillance program will develop fieldable, low-cost gene editing-based diagnostics capabilities for rapid, specific, sensitive, and multiplexed detection of biological threats in military and public health scenarios. This program will investigate the design rules for diagnostic and biosurveillance targets to achieve broad-spectrum detection with high confidence diagnostic results. These design rules will inform advanced computational and machine learning approaches to scan genome data and algorithmically design probes and guides for optimal assay results. Additional work will develop assay architectures, reagents, and detection platforms to enable field-forward diagnostics at the point-of-care with the same sensitivity, and reliability tests conducted in hospital/central laboratories.
Document Details
- Document Type
- Accomplishment
- Publication Date
- Oct 01, 2021
- Source ID
- e146747ba5e9e43206c3f5317c13d6e0