8) Host Response - Enhanced Biodefense (ENBD)
Abstract
This effort will focus on Advanced Pathogen and Emerging Threat Characterization with attention on characterizing host responses and pathogen signatures using multi-omic analyses and enabling technologies to develop the ability to characterize known and emerging threats. This effort will include understanding the host response to various pathogen insults to identify patterns of response that allow for the prediction of novel threat agents based on the host responses they generate. Evaluations of pathogenesis and viral transmission to understand differences in disease severity will also be conducted. Within this program, efforts to characterize synthetic and natural viral pathogens to compare varying gene expressions between the two will be executed. This program accelerates the ability to characterize emerging threats and will generate more robust data sets for training threat agnostic tools to provide better characterization capabilities.
Document Details
- Document Type
- Accomplishment
- Publication Date
- Oct 01, 2023
- Source ID
- f2ff1a8d932c907256e39f4fd413066f