Controlled Genome Protection
Abstract
The Controlled Genome Protection program will develop advanced capabilities to control and tune the activity of gene editing technologies. This research leverages previous investment in Genome Protection Technologies-developed laboratory tools to prevent or limit unintended genome editing or engineering. Advances in synthetic and environmental biology have significantly expanded the suite of genome editors and modulators available. Many of the new genome editors have been identified from rare, slow-growing microorganisms with unique metabolic capabilities. New tools, both highly specific as well as broadly acting across these new classes of genome editors, are required to advance our understanding of, our control of, and ultimately our leverage of gene editing technologies across all domains of life. Advances within this program will ensure that the U.S. leads innovation in this widespread, advancing field that poses potential national security threats due to the large-scale democratization of gene editing technologies.
Document Details
- Document Type
- Accomplishment
- Publication Date
- Oct 01, 2025
- Source ID
- fa58547eef2326ba81cf066224bb5d35
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- Root: BIOMEDICAL TECHNOLOGY