Applied Research on drugs and vaccines against parasitic diseases

Abstract

This effort assesses and improves on candidate drugs coming from the Department of Defense (DoD) discovery program and from other collaborations for prevention and treatment of malaria; to counter the continuing spread of drug resistance to current drugs; assesses currently available drugs for use against cutaneous leishmaniasis (a skin-based disease transmitted by sand flies) in animal models; and select the most effective and safe candidates for continued refinement and possible clinical testing. This effort also conducts studies to investigate new candidate vaccines for preventing malaria and selects the best candidate(s) for continued refinement. A highly effective vaccine would reduce or eliminate the use of anti-malarial drugs and would minimize the progression and impact of drug resistance to current/future drugs.

Document Details

Document Type
Accomplishment
Publication Date
Oct 01, 2020
Source ID
9f355f20cedf0ce858f04881caca03d7

Tags

Fields of Study

  • Medicine

Readers

  • Infectious Disease/Epidemiology
  • Military Science and Technology Research and Modernization.
  • Parasitology and Pharmacology of Malaria.

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech

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