Medical Technology
Abstract
This PE supports application of knowledge gained through basic research to refine drugs, vaccines, medical devices, diagnostics, medical practices/ procedures, and other preventive measures essential to the protection and sustainment of Warfighter health. Research is conducted in five principal areas: Combat Casualty Care, Military Operational Medicine, Military Relevant Infectious Diseases, Clinical and Rehabilitative Medicine, Medical Capabilities to Support Dispersed Operations, and Systems Biology/Network Sciences. Project 869 Warfighter Health Prot & Perf Stnds Description: Refines knowledge and technologies on screening tools and preventive measures for post-traumatic stress disorder (PTSD) and behavioral health problems (e.g., suicide, substance abuse) and mild traumatic brain injuries, physiological monitors, and interventions to protect Warfighters from injuries resulting from operational stress, and exposure to hazardous environments and materials. Also conducts research on medically valid testing devices (i.e., the test mannequins that are true to the human form and physiologically and anatomically accurate) and predictive models used for the refinement of Warfighter protective equipment. This Project is being coordinated with the Defense Health Agency. Project 870 Dod Med Def Ag Inf Dis Description: Designs and refines drugs, vaccines, medical diagnostic assays/tests devices, other preventive measures for protection and treatment against naturally occurring infectious diseases as identified by worldwide medical surveillance and military threat analysis. This Project is being coordinated with the Defense Health Agency. Project 874 Cbt Casualty Care Tech Description: Identifies and evaluates drugs, biologics (medical products derived from living organisms), medical devices, and associated clinical practices for field trauma care systems, resuscitation, and life support, with emphasis on provision of prolonged field care when medical evacuation and access to definitive surgical care is delayed. Focus is identification of more effective critical care technologies and clinical practices to treat severe bleeding, traumatic brain injury, burns and other combat related injuries. This Project is being coordinated with the Defense Health Agency. Project ET4 Appl Resch in Clinical and Rehabilitative Medicine Description: Identifies and evaluates drugs, biologics, medical devices, treatments and diagnostics for post-evacuation restorative, regenerative and rehabilitative care, as well as systems for use by field medics and surgeons for ocular trauma. Research focus is on identifying more effective technologies and protocols to treat ocular injury and visual system dysfunction, as well as laboratory and animal studies for regenerating skin, muscle, nerves, vascular and bone tissues for the care and treatment of wounded Service Members. This Project is coordinated with the Defense Health Agency. Project VB4 System Biology and Network Science Technology Description: Includes strategic oversight, direction and management of applied research in integrative systems biology of military relevant conditions, and the Systems Biology Collaboration Center (SBCC). The SysBioCube (a biomedical research data integration and analysis system), managed by the SBCC, provides the ability for multi-site collaborative efforts to integrate, visualize and evaluate complex data using innovative technologies. Post-Traumatic Stress Disorder and coagulopathy (a disorder that impairs the blood's ability to form clots) projects have utilized the systems biology analytical and visualization within the SysBioCube to inform the development of prognostic indicators, objective diagnostics, and improved and personalized therapeutic strategies more quickly than non-systems approaches. The SBCC also serves as a Medical Research Materiel Command (MRMC) resource for data sharing and data management for maximizing the value of all research efforts across the Command. Project XV5 Medical Capabilities to Support Dispersed Ops Description: Research to design, develop, and improve medical robotic and autonomous systems (Med-RAS), Virtual Health for telemedicine and remotely delivered patient care, and unmanned capabilities of providing or supporting combat casualty care in far-forward and dispersed geographic environments. This research includes the design of semi-autonomous and closed-loop combat casualty triage, diagnosis, physiological monitoring, therapeutic intervention, casualty evacuation, telemedicine/tele-mentoring and emergency medical resupply technologies for integration with emerging multi-purpose Army Robotics and Autonomous Systems (RAS) and Virtual Health/Telemedicine delivery platforms while optimizing the medical logistic footprint. Project MK4 Warfighter Health Applied Rsch Technology Description: Refines knowledge and technologies on screening tools and preventive measures for PTSD, behavioral health problems, and mild traumatic brain injuries, physiological monitors, and interventions to protect Warfighters from injuries resulting from operational stress and exposure to hazardous environments and materials. Also conducts research on medically valid testing devices and predictive models used for the refinement of Warfighter protective equipment. Project MM4 Cbt Casualty Care Applied Rsch Technology Description: Identifies and evaluates drugs, biologics (medical products derived from living organisms), medical devices and associated clinical practices for field trauma care, resuscitation, and life support with emphasis on provision of prolonged field care when medical evacuation and access to definitive surgical care is delayed. Focus is identification of more effective critical care technologies and clinical practices to treat severe bleeding, traumatic brain injury, burns and other combat related injuries. Project MM8 Infectious Diseases Applied Rsch Technology Description: Applied research to design and refine drugs, vaccines, and other medical countermeasures against naturally occurring infectious diseases as identified by worldwide medical surveillance and capability needs assessments. Project MN1 Applied Sensory Systems Trauma Technology Description: Research to understand the influence of stress on the effectiveness of pain relief drugs (analgesics). This Project conducts laboratory and animal studies for the purpose of developing novel, non-opioid drugs to treat pain in the austere battlefield environment with minimal side effects. The cited work is consistent with the Assistant Secretary of Defense, Research and Engineering Science and Technology, focus areas and the Army Modernization Strategy. Work in this PE is performed by the United States Army Medical Research Materiel Command (USAMRMC), Fort Detrick, MD. All medical applied research is conducted in compliance with Food and Drug Administration (FDA) or Environmental Protection Agency (EPA) regulations. The FDA requires thorough testing in animals (preclinical testing) to ensure safety and, where possible, effectiveness prior to evaluation in controlled human clinical trials (upon transition to Advanced Technology Development). This PE focuses on research and refinement of technologies such as product formulation and purification and laboratory test refinement with the aim of identifying candidate solutions. This work often involves testing in animal models. The EPA also requires thorough testing of products, such as sterilants, disinfectants, repellents, and insecticides to ensure the environment is adequately protected before these products are licensed for use. Program refinement and execution is externally peer-reviewed and fully coordinated with all Services as well as other agencies through the Joint Technology Coordinating Groups of the Armed Services Biomedical Research Evaluation and Management (ASBREM) Community of Interest (COI). The ASBREM COI, formed under the authority of the Assistant Secretary of Defense for Research and Engineering, serves to facilitate coordination and prevent unnecessary duplication of effort within the Department of Defenses (DoD) biomedical research and refinement community, as well as their associated enabling research areas.
Document Details
- Document Type
- R2 Budgetary Justification
- Publication Date
- Oct 01, 2020
- Source ID
- 0602787A_2_2040_PB_2020
- Change Summary Explanation
- Service Agency Name
- Army
Entities
Organizations
- United States Army
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