DETERMINATION OF CARBOXYHEMOGLOBIN IN DECOMPOSED BODIES

Abstract

The interpretation and the significance of carbon monoxide findings in cases associated with decomposition is studied. The evidence presented indicates that the percentage of carboxyhemoglobin saturation value is not markedly altered during postmortem decomposition when: (1) the specimens are properly preserved, and (2) the blood extracted from tissue is examined as soon as possible for the presence of carbon monoxide. It appears possible to obtain carbon monoxide values, utilizing blood extracted from tissue, in the presence of postmortem decomposition that are similar to the antemortem levels. For example, within the 4% to 12% carboxyhemoglobinsaturation range covered, there was neither a marked increase nor decrease in final percentage of carboxyhemoglobin following decomposition. Nevertheless, unreliable carboxyhemoglobin saturation values may occur. A gas-solid chromatographic procedure for determining carbon monoxide using blood or tissue is presented. This procedure employs a Van Slyke apparatus for liberating gases from biological specimens modified for introducing released gas into the gas chromatograph.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1963
Accession Number
AD0420631

Entities

People

  • Abel M. Dominguez
  • James R. Halstead
  • Thaddeus J. Domanski

Organizations

  • Armed Forces Institute of Pathology

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Accident Investigations
  • Accidents
  • Air Force
  • Aircrafts
  • Aviation Accidents
  • Biomedical Research
  • Carbon Monoxide
  • Chromatographs
  • Decomposition
  • Dielectric Gases
  • Fluids
  • Gases
  • Materials
  • Materials Laboratories
  • Saturation
  • Sea Water
  • Thorax

Fields of Study

  • Biology

Readers

  • Analytical Chemistry
  • Electrochemical Engineering/ Fuel Cell Technologies
  • Mathematics or Statistics