EXPLORATION OF NEW CHEMOTHERAPEUTICS FOR INFECTIOUS DISEASES
Abstract
Protomycin, a new antiamaebic substance was producted by a new strain Sterptomyces reticuli var. protomycicus, was determined chemical properties and structure. Next subjects are planted the mass production of Protonycin, subsequently treated amaebic patients with it. As a new other antibacterial and antifungal susstance was fund in this Streptomyces cultural media the substance was tried to purify and crystallize at the present time. Finally a antibacterial substance was crystallized as a colorless needle crystaline substance. Antimicrobial activity of this crystaline substance: The minimal inhibitory concentration of the substance was 1 mcg/ml - 1,000 mcg/ml to gram positive bacteria, but this dis not show inhibitory effects to gram negative bacteria.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 19, 1963
- Accession Number
- AD0439309
Entities
People
- Toju Hata