METABOLIC STUDIES OF ENERGY DENSE COMPOUNDS FOR AEROSPACE NUTRITION

Abstract

The aim of these studies was the development of model compounds with which information useful in understanding energy metabolism might be obtained to aid in development of food for space travel. Seven-month studies feeding rats with 1,3-butanediol have been completed. The results of these studies confirm the utilization of this compound as an energy source. Measurement of a number of metabolic parameters at the completion of the study support the contention that 1,3-butanediol is probably metabolized through carbohydrate rather than fat pathways. Metabolism studies with 2,4-dimethylheptanoic acid labeled with C14 in the alpha methyl group indicate that this compound as predicted is oxidized through propionate. Design and construction details of the direct animal calorimeter are presented. Results of a limited number of studies with rats fed various diets indicate that the device fulfills its design functions.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1965
Accession Number
AD0623615

Entities

People

  • H. A. Dymsza
  • S. A. Goldblith
  • S. R. Tannenbaum
  • Stephanie Miller

Organizations

  • Massachusetts Institute of Technology

Tags

Communities of Interest

  • Biomedical
  • Energy and Power Technologies
  • Ground and Sea Platforms

DTIC Thesaurus Topics

  • Alkanes
  • Body Weight
  • Calorimeters
  • Carbohydrates
  • Carboxylic Acids
  • Chemical Synthesis
  • Chemistry
  • Esters
  • Ethers
  • Fatty Acids
  • Food
  • Heat Energy
  • Ketones
  • Measurement
  • Metabolism
  • Nutrition
  • Organic Chemistry

Readers

  • Analytical Chemistry
  • Cardiovascular Physiology
  • Exercise and Sports Science.

Technology Areas

  • Space