SEPARATION OF ADENOVIRUSES INTO SUBGROUPS IN CONNECTION WITH THEIR HEMAGGLUTINATING ACTIVITY AND THE PROPERTIES OF THE HEMAGGLUTININS
Abstract
Of the adenovirus serotypes 8-10, 13, 15, 17, 19, 22-24, 26, and 27, which agglutinate rat erythrocytes, types 8, 9, 10, and 19 also agglutinate erythrocytes of human blood group 0, mice, and guinea pigs, types 13, 26, and 27 - erythrocytes of human blood group 0 and mice, and serotypes 15, 17, 22, 23, and 24 - erythrocytes of mice. In adenoviruses of types 3, 7, 14, 20, and 25, which agglutinate monkey erythrocytes, a dependence is observed in the titers of hemagglutinins on the individual peculiarities of rhesus monkey erythrocytes, and in type 21 - on the individual peculiarities of Grivet monkey erythrocytes. In types 11 and 16 no variations were observed in the titers of hemagglutinins depending on the individual peculiarities of erythrocytes from individual specimens of monkeys. The most sensitive for type 3 are erythrocytes of Grivet monkeys, and for types 7, 14, 20, 21, and 25- rhesus monkeys. Serotypes 11 and 16 agglutinate the erythrocytes of both species of monkeys equally well. Differences were revealed in the agglutinating activity of reference strain 21 and the strain No 167 which was freshly isolated by us. Both agglutinated erythrocytes of the rhesus monkey; erythrocytes of Grivet monkeys were agglutinated only by the reference strain.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1968
- Accession Number
- AD0675859
Entities
People
- E. E. Zolotarskaya
- R. S. Dreizin
Organizations
- United States Army Biological Warfare Laboratories