The Toxicology of Cyclotrimethylene-trinitramine (RDX) and Cyclotetramethylene-tetranitramine (HMX) Solutions in Dimethylsulfoxide (DMSO), Cyclohexanone, and Acetone

Abstract

A study of the toxicology of the explosives cyclotrimethylene- trinitramine (RDX) and cyclotetramethylene-tetranitramine (HMX) in acetone, cyclohexanone, and pure and technical grade dimethysulfoxide (DMSO) was initiated to establish whether there is any danger to plant personnel that handle such mixtures. The report contains a review of the existing literature on each explosive and on each solvent. It also describes tests that were conducted to establish the intravenous toxicity of the explosives in DMSO, the skin effects, the pharmacological effects, the sensitization potential, and the ocular effects of the explosives in each solvent. All of these tests were conducted on animals.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1974
Accession Number
AD0780010

Entities

People

  • Bernard P. Mcnamara
  • David G. Fairchild
  • Donald K. Biskup
  • Edmund J. Owens
  • Harold P. Averill
  • Henry P. Cluchta
  • John F. Callahan
  • Roy H. Rengstorff

Tags

DTIC Thesaurus Topics

  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • Medical Personnel
  • Rdx
  • Rodents
  • Skin Diseases

Fields of Study

  • Chemistry

Readers

  • Agricultural Chemistry/Soil Science
  • Analytical Chemistry
  • Neurotrauma and Rehabilitation Medicine.