The Clinical Aspects of Rift Valley Fever Virus in Household Pets: 1. Susceptibility of the Dog
Abstract
The dog was shown to be susceptible to Rift Valley fever virus (RVFV) . Death occurred in all animals of 1 and 7 days of age inoculated with 1 x 10 to the 2.2 power MICLD50 or more of virus, and two of four puppies died following inoculation with 1 x 10 to the 0.2 power MICLD50 of virus. Temperature at death was hypothermic. Older animals, although susceptible, were not killed by RVFV; there were no signs of clinical illness, although 50% of adult dogs developed a viremia. All animals with a positive viremia demonstrated a positive serum neutralization titer. Transmission of RVFV from pup to mother and from pup to pup was demonstrated. There was evidence that antibodies were passed from mother to pup in the colostrum. The data suggest an effect on fertility. The epidemiological aspects of this study are discussed. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1968
- Accession Number
- AD0846267
Entities
People
- Edward L. Stephan
- Frederick Klein
- Jerry S. Walker
- John Q. Mitten
- Leonard G. Schuh
- Norman S. Remmele
- Richard C. Carter