A Comparison of Mechanical Tetracycline Disinfection of Osseotite and Nanotite Implant Surfaces in a Simulated Model of Peri-implantitis

Abstract

This pilot study will evaluate the efficacy of tetracycline in decontaminating OSSEOTITE and Nanotite implants within a simulated intrabony defect model. Implants will be secured in a sterilized resin model and contaminated with S. Sanguinis grown in a biofilm solution. Following incubation, tetracycline will be applied with cotton pellets in a standardized fashion, and residual bacteria will be put into solution and plated on blood agar plates. Final CFU counts will be tabulated allowing for a comparison of the ability to decontaminate OSSEOTITE versus Nanotite surfaces within a unique in vitro model. Positive and negative controls will be included for comparison.

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Document Details

Document Type
Technical Report
Publication Date
Aug 14, 2013
Accession Number
AD1013019

Entities

People

  • Keith R. Merchant

Organizations

  • Uniformed Services University of the Health Sciences

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacteria
  • Citric Acid
  • Materials
  • Medical Personnel
  • Microbiology
  • Microbiomes
  • Mouth Diseases
  • Osteoporosis
  • Periodontics
  • Pilot Studies
  • Prostheses And Implants
  • Prosthetics
  • Surgery
  • Teeth

Readers

  • Microbial Pathology
  • Toxicology/Environmental Toxicology
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology