Large Extremity Peripheral Nerve Repair in Nonhuman Primate Models
Abstract
The aim of this JWMRP proposal is to employ a relevant large animal model of peripheral nerve injury involving large segmental deficit in the upper limbs that recapitulates human anatomy and is capable of objective functional outcome testing that is not possible in other large animal models. With this model we will determine whether our improved method of restoring continuity to peripheral nerves by photosealing a commercial a cellular nerve allograft across the deficit can produce outcomes equivalent to standard of care autologous grafting for wounded warfighters that do not have sufficient autologous donor nerve due to extensive combat trauma. Improving functional recovery for wounded warfighters in this manner would have a major impact on quality of life and wellbeing of such wounded warfighters.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2018
- Accession Number
- AD1060234
Entities
People
- Robert W Redmond
Organizations
- Massachusetts General Hospital