Protein Modeling with X-ray Scatter Data

Abstract

In principle, X-ray scattering could provide an alternative means to characterize the structure of proteins that do not form clean periodic crystals. In this work, we compute radial distribution functions from three known X-ray protein crystal structures (green fluorescent protein, bovine serum albumin, and hen egg white lysozyme), and compare them to acquired X-ray scattering data on the target proteins.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2018
Accession Number
AD1063541

Entities

People

  • Mark H Griep
  • Michael S. Lee
  • Nick Bedford
  • Sasha Teymorian

Organizations

  • United States Army Research Laboratory

Tags

Communities of Interest

  • Autonomy
  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Albumins
  • Crystal Structure
  • Crystallography
  • Crystals
  • Distribution Functions
  • Electron Density
  • Electrons
  • Grids
  • Military Research
  • Molecules
  • Muramidase
  • Proteins
  • Scattering
  • Three Dimensional
  • X Ray Scattering
  • X Rays
  • X-Ray Crystallography

Fields of Study

  • Physics

Readers

  • Oncology (Cancer Research).
  • Solar Physics
  • Toxicology/Environmental Toxicology